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Building a secure and low-code bioinformatics workbench on AWS HealthOmics

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The article describes a solution for building a secure and low-code bioinformatics workbench on AWS HealthOmics, a suite of services for storing, querying, analyzing, and generating insights from genomic and other biological data. The solution was developed through a collaboration between Singapore General Hospital, SingHealth Office of Academic Informatics, and Amazon Web Services.

Specifically, the article covers:

  • Challenges faced in traditional on-premises environments for processing large genomic datasets
  • Overview of AWS HealthOmics and its components: HealthOmics storage, HealthOmics analytics, and HealthOmics Workflows
  • Workflow dependencies pipeline for pulling required containers, scanning for vulnerabilities, and pushing to Amazon ECR
  • AWS HealthOmics private workflow pipeline for automating the deployment of private workflows
  • Event-driven architecture for real-time notifications on workflow status using Amazon EventBridge and Amazon SNS
  • Conclusion highlighting the benefits of the solution, such as streamlining workflow deployment, ensuring security through vulnerability scanning, and enabling version control for workflows and containers


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