How NIH scientists unlocked cardiovascular disease insights using AWS
Public Sector Blog
NIH scientists used AWS cloud infrastructure to make a breakthrough in understanding how low-density lipoprotein (LDL) interacts with its receptor, potentially leading to more personalized cardiovascular disease treatments.
- Processed over 35,000 molecular movies per dataset, managing 17.5TB of raw data
- Used cryogenic electron microscopy (cryo-EM) to visualize biomolecular structures
- Accelerated research completion from 2-3 years to just 12 months
- Achieved up to 12 times faster processing speeds compared to on-premises systems
- Enabled real-time collaboration among research teams
The research, published in Nature, utilized AWS services like Direct Connect, FSx, S3, and GPU-enabled computing to successfully determine the structure of LDL and its receptor, potentially leading to more targeted cholesterol treatments.
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