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Powering genetic rare disease diagnostics with AWS at Hannover Medical School (MHH)

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Hannover Medical School (MHH) has developed an innovative AWS-powered solution for genetic rare disease diagnostics, addressing computational challenges in whole genome sequencing (WGS).

  • Implemented a cloud-based workflow for re-analyzing genomic data using Amazon S3, EC2, and AWS Batch
  • Enables flexible analysis of complex genetic cases, particularly in pediatric diagnostics
  • Reduces sample processing time to about an hour, up to 4-8 times faster than traditional methods
  • Cost-effective at approximately $20 per genome analysis with pay-as-you-go pricing
  • Maintains data privacy and security compliance with German healthcare regulations

The solution provides a hybrid approach to genetic analysis, offering scalability, efficiency, and advanced diagnostic capabilities for medical research and patient care.



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