Exact Sciences Transforms Bioinformatics Infrastructure with AWS HealthOmics

This article details how Exact Sciences transformed its bioinformatics infrastructure using AWS HealthOmics to process cancer diagnostic data more efficiently.

• Exact Sciences processes massive NGS datasets equivalent to 1,000+ HD movies per flow cell
• Legacy infrastructure had fragmented systems, high maintenance costs, and poor cost visibility
• AWS HealthOmics provides fully managed bioinformatics workflows with automated resource management
• Event-driven architecture integrates with Amazon EventBridge for asynchronous component communication
• Achieved significant cost reduction while maintaining performance, accuracy, and throughput
• Improved resource visibility through CloudWatch monitoring and HealthOmics console access
• Accelerated development cycles and simplified onboarding for new team members
• HealthOmics Run Analyzer enables detailed pipeline cost and resource analysis per task

Exact Sciences successfully reduced operational complexity and costs by migrating to AWS HealthOmics, allowing the team to focus on cancer diagnostics innovation rather than infrastructure management.