Submit up to 100,000 Bioinformatics Workflow Runs with a Single API Call in AWS HealthOmics

This article announces AWS HealthOmics batch runs, enabling submission of up to 100,000 bioinformatics workflow runs with a single API call.

• Submit up to 100,000 runs in one StartRunBatch API request instead of individually
• Define shared configuration once with per-run overrides for sample-specific parameters
• Inline settings for batches up to 100 runs; S3 JSON file for larger batches
• Asynchronous gradual submission eliminates need for custom throttling logic
• Track batch status and individual run progress via GetBatch and ListRunsInBatch APIs
• Cancel, delete, or manage entire batches with single API calls
• Reduces hundreds of lines of submission and retry code

Batch runs simplify large-scale genomics workflow submission, allowing researchers to focus on scientific discovery rather than infrastructure management.