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AWS HealthOmics now supports Nextflow version pinning at run time

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This article announces that AWS HealthOmics now supports Nextflow version pinning at run time, allowing customers to specify the Nextflow engine version via the StartRun API.

  • Customers can pin runs to specific Nextflow versions for controlled migration
  • Supported versions include 22.04, 23.10, 24.10, 25.10, and 26.04
  • StartRun API parameter takes precedence over workflow manifest specifications
  • Test workflows across multiple engine versions without modifying source code
  • Production workflows stay on validated versions while development tests newer versions
  • Reduces risk in regulated environments requiring pipeline validation
  • Available in all AWS HealthOmics regions globally

This feature enables safer Nextflow version upgrades by allowing parallel testing and validation before production deployment.



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